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Cancer Cell Isolation & Characterization

Laser Force Cytology™ (LFC), rapid viral infectivity assay data correlates tightly with traditional plaque and TCID50 assays. Radiance® provides new information around host response and the viral life cycle, enabling a better understanding of cellular infection through the measurement of novel phenotypic changes.

  • Detects T-cell activation in a label-free manner

  • Quantifies response of tumor cells to drug candidates using label-free CTC analysis

  • Identifies, characterizes, and sorts cancerous cell phenotypes

  • Quantitatively measures the changes in the cell’s cytoskeleton which is known to correlate with metastatic potential

Detecting And Characterizing Tumor Cells Is Critical For CTC Analysis

  • Tumor cells change and display tremendous heterogeneity

  • Current cell sorting methods use antibodies for detection, but are inadequate as antigens can change over time, between patients, and after treatment

  • Circulating tumor cells (CTCs) are important rare cells that are crucial for understanding cancer biology and have great diagnostic value and are difficult to reliably detect using antibody-based methods.

  • Drug companies can use LumaCyte’s Radiance instrument to understand changes in cell phenotype in response to drug candidates in pre-clinical research and testing

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